Granzyme B is able to induce target cell apoptosis by activating caspase independent pathways. Granzyme B is induced in CD8+ T lymphocytes with ConA/ IL-2 and CD4+ T lymphocytes with anti CD3/CD28 or CD3/CD46.
|Storage||Store in the dark at 2-8°C.|
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).
Human NK cell line YT-INDY-derived granzyme B.
Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.