CD16 (Clone GRM1)

SKU: P16F-100T Categories: ,

209,30 € excl.VAT – 523,26 € excl.VAT

This antibody reacts with the CD16- antigen (the Fc gamma receptor II), which is expressed on granulocytes, NK lymphocytes and macrophages. The mobility of the CD16-antigen is dependent on the NA1/NA2 allotype of the neutrophil donor. The monoclonal antibody inhibits the binding of human IgG to the Fc gamma receptor II.

Additional information

Conjugated

,

Size

,

Regulatory Status

Clone

Gene ID

Format

Species Reactivity

Isotype

Tested Applications

Clonality

UniProt

Mw

Population

Dendrititic Cell, Granulocyte, Macrophage/Monocyte, NK Cell, T-Cell
Storage Store in the dark at 2-8°C.
Other names

FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3.
Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).
Immunogen

Normal human peripheral blood granulocytes.
Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.

Recomended usage

CD16 clone GRM1, mAb is used for identify/enumerate human antigen (FcRIII). GRM1 recognizes NA2-FcRIIIb & FcRIIIa whereas clone 3G8 is an antipan FcγRIII. It´s effective for direct IF staining of human tissue for FCM tests using ≤1 μg/10^6 cells.

Resources

Technical Data Sheet (TDS) – (English)

Safety Sheet (MSDS) – (English)

References

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Product descriptionReferenceTitleAuthorsJournalYear

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