CD59 (Clone VJ1/12,2)

SKU: P59F-100T Categories: ,

209,30 € excl.VAT – 544,81 € excl.VAT

This antibody reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).

Additional information

Conjugated

, , ,

Size

,

Regulatory Status

Clone

Gene ID

Format

Species Reactivity

Isotype

Tested Applications

Clonality

UniProt

Mw

Population

Erythrocyte, Granulocyte, Macrophage/Monocyte, NK Cell, T-Cell
Storage Store in the dark at 2-8°C.
Other names

1F-5Ag, H19, HRF20, MACIF, MIRL, P-18, PROTECTIN, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC-2.4.1.135, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA.
Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).
Immunogen

Human Tissue / cell preparation (peripheral blood lymphocytes).
Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.

Recomended usage

CD59, clone VJ1/12,2 , is a mAb used for the idenfitication of CD59 protein expressed on all hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.

Resources

Technical Data Sheet (TDS) – (English)

Safety Sheet (MSDS) – (English)

References

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Product descriptionReferenceTitleAuthorsJournalYear

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