CD3/CD8/CD45/CD4

SKU: 3F18PE145PP14A-50T Categories: ,

563,99  excl.VAT

The CD3 monoclonal antibody is directed against the CD3- antigen (T3-antigen), which is expressed on human T lymphocytes. The monoclonal antibody reacts with 80-90% human peripheral T lymphocytes and medullary thymocytes. The monoclonal antibody does not react with B-cells, monocytes, granulocytes and platelets. The monoclonal antibody is mitogenic for resting T lymphocytes and it blocks the cytolytic activity of CTL clones.
The CD8 monoclonal antibody is directed against the CD8-antigen (T8-antigen),which is expressed on human T lymphocytes. The monoclonal antibody reacts with 20-30% of human peripheral T lymphocytes.
The CD45 monoclonal antibody is directed against the CD45- antigen, defined T200 or Leucocyte Common Antigen. The antibody reacts with all cells of the haemopoietic lineage, not with cells of other lineages.
The CD4 monoclonal antibody is directed against the CD4-antigen (T4-antigen), which is expressed on human peripheral T lymphocytes and 80% of thymocytes. The monoclonal antibody reacts on a low level with human monocytes and macrophages.

Additional information

Conjugated

Size

Clone

Format

Species Reactivity

Isotype

Tested Applications

Regulatory Status

Storage Store in the dark at 2-8°C.
Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).

Immunogen

The anti-CD3 monoclonal antibody
derives from human leukocytes.
The anti-CD8 monoclonal antibody derives from human T cells.
The anti-CD45 monoclonal antibody derives from T cells from leukemic HPB-ALL.
The anti-CD4 monoclonal antibody derives from T cells from leukemic HPB-ALL.

Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.