StarBright™ Dyes, the next generation of clinical flow cytometry dyes

At Immunostep we remain committed to innovation as a driver to provide more accurate, robust and tailored diagnostic solutions to meet the real needs of clinical laboratories and research centres. In line with this commitment, we are excited to announce our new launch: the addition of Bio-Rad’s StarBright™ fluorescent dyes to our range of IVD reagents for flow cytometry.

Thanks to a licensing agreement with Bio-Rad Laboratories, Inc. a globally recognised developer of life science and clinical diagnostic technologies, our products will take a quantum leap forward in terms of performance, reliability and versatility.

What are StarBright™ Dyes?

StarBright™ Dyes are an innovative family of fluorescent dyes specifically designed for multi-parametric flow cytometry applications. They have been developed by Bio-Rad with the aim of overcoming some of the traditional limitations of conventional dyes, such as spectral overlap or low stability.

Thanks to their advanced optical properties, these dyes allow:

• High signal intensity, even at low levels of antigenic expression.
• Exceptional stability, making them ideal for reproducible clinical assays.
• Narrow, sharp spectra, reducing spillover and improving compensation.
• Compatibility with standard lasers, making them easy to integrate into existing equipment.

These features make StarBright™ especially useful for designing complex multi-marker panels, without compromising clarity or resolution.

What are the benefits of our IVD reagents?

At Immunostep we apply StarBright™ Dyes to the development of reagents for clinical flow cytometry diagnostics, optimised to ensure consistent, fast and clinically relevant results. Some of the key benefits of these new dyes include:

• Improved discrimination of cell subpopulations, key for monitoring immunological and haematological diseases.
• Significant reduction of background noise and spectral interference, facilitating the interpretation of results.
• Increased robustness in customised panels, even in configurations of more than 8-10 parameters.

This technology also represents a significant improvement in process automation and data quality for clinical reporting.

Clinical applications: more accurate diagnosis in key areas

The addition of StarBright™ Dyes to our IVD reagents has a direct impact in several high-value clinical areas:

• Oncology: They facilitate the identification of relevant tumour markers and cell populations for the classification and monitoring of different types of cancer.
• Immunology: They allow a finer analysis of lymphocyte subpopulations, useful for the diagnosis of immunodeficiencies, autoimmune diseases and immunomodulatory therapies.
• Haematology: Improve the analysis of haematopoietic stem cells, progenitors and abnormal populations, such as in leukaemias or myelodysplastic syndromes.
• Infectious diseases: Facilitate immune monitoring in patients with chronic infections or complex inflammatory states.

A step forward in advanced diagnostics

As our CEO Ricardo Jara explains: “The integration of StarBright™ technology reinforces our mission to continue developing reliable, high-precision and clinically relevant diagnostic solutions for laboratories around the world.”

This alliance represents a qualitative leap not only in the technical quality of our products, but also in the ability to adapt to the needs of the real clinical environment, where sensitivity, reproducibility and robustness are essential.

Interested to know more?

We are already incorporating StarBright™ Dyes into several IVD reagent lines available for clinical flow cytometry. Whether you are developing custom panels, validating new biomarkers or simply want to improve the resolution of your current assays, we invite you to find out more.

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📩 And if you need more technical information, product sheets or personalised advice, do not hesitate to contact us at info@immunostep.com. Our team will be happy to help you.