196,00 € – 246,00 €
This antibody reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).
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Storage | Store in the dark at 2-8°C. |
Other names | 1F-5Ag, H19, HRF20, MACIF, MIRL, P-18, PROTECTIN, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC-2.4.1.135, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA. |
Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3). |
Immunogen | Human Tissue / cell preparation (peripheral blood lymphocytes). |
Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml. |
CD59, clone VJ1/12,2 , is a mAb used for the idenfitication of CD59 protein expressed on all hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.
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