CD59 (Clone MEM-43)

SKU: 59PE1-100T Categories: ,

345,76 € excl.VAT

Antibody CD59 (Clone MEM-43) reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).

Additional information

Conjugated

Size

Clone

Gene ID

Format

Species Reactivity

Isotype

Tested Applications

Clonality

Regulatory Status

UniProt

Mw

Storage Store in the dark at 2-8°C.
Other names

1F-5Ag, H19, HRF20, MACIF, MIRL, P-18, PROTECTIN, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC-2.4.1.135, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA.
Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).
Immunogen

Thymocytes and T lymphocytes.
Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.

Recomended usage

CD59 (Clone MEM-43) is a mAb used for the idenfitication of CD59 protein expressed on all hematopoietic cells. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.

Resources

Technical Data Sheet (TDS) – (English)

Safety Sheet (MSDS) – (English)

References

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Product descriptionReferenceTitleAuthorsJournalYear

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