CD38 (Clone HB7)

SKU: P38F2-100T Categories: ,

212,67 517,08  VAT excl.

The HB7 monoclonal antibody reacts with the human CD38 molecule, a type II transmembrane protein. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cell. The CD38 antigen acts as a bifunctional ectoenzyme that catalyzes both the synthesis and the hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signaling pathways.

Additional information

Conjugated

, , ,

Size

Regulatory Status

Clone

Gene ID

Format

Species Reactivity

Isotype

,

Tested Applications

Clonality

UniProt

Mw

Storage Store in the dark at 2-8°C.
Other names

T10, ADPribosyl cyclase, and cyclic ADP ribose hydrolase 1.

Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).

Immunogen

The anti-CD38 monoclonal antibody derives from BJAB human B cell line.

Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.