196,00 € – 496,00 €
The HB7 monoclonal antibody reacts with the human CD38 molecule, a type II transmembrane protein. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cell. The CD38 antigen acts as a bifunctional ectoenzyme that catalyzes both the synthesis and the hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signaling pathways.
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Storage | Store in the dark at 2-8°C. |
Other names | T10, ADPribosyl cyclase, and cyclic ADP ribose hydrolase 1. |
Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3). |
Immunogen | The anti-CD38 monoclonal antibody derives from BJAB human B cell line. |
Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml. |
Immunostep’s CD38, clone HB7, is a monoclonal antibody intended for the identification and enumeration of plasma cells using flow cytometry. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 1 test for 10^6 cells.
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