155,00 € excl.VAT – 450,00 € excl.VAT
This antibody reacts with the CD16-antigen. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide-anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor. FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates. Binding of IgG leads to activation of signal transduction pathways, resulting in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, cytokine release, and antigen presentation.
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Volume | 1 μg/test, 2 μL/test, 20 μL/test |
Storage | Store in the dark at 2-8°C. |
Other names | FCRIII, Fc-gamma receptor IIIb, CD16, FCG3, FCGR3, IGFR4. |
Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3). |
Immunogen | Human polymorphonuclear leukocytes. |
Concentration | 0,05 mg/ml, 2 mg/ml |
CD16 clone 3G8, mAb is used for identify/enumerate human antigen (FcRIII). It´s an antipan FcγRIII (CD16) whereas clone GRM1 recognizes NA2-FcRIIIb & FcRIIIa. It´s effective for direct IF staining of human tissue for FCM tests using ≤1 μg/10^6 cells.
Technical Data Sheet (TDS) (CE-IVD) – (English)
Hoja Técnica (TDS) (CE-IVD) – (Español)
Technical Data Sheet (TDS) (RUO) – (English)
Safety Sheet (MSDS) (CE-IVD) – (English)
Ficha de Seguridad (MSDS) (CE-IVD) – (Español)
Safety Sheet (MSDS) (RUO) – (English)
Safety Sheet (MSDS) (Purified) (RUO) – (English)
Instruction for Use (IFU) (CE-IVD) – (German)
Instruction for Use (IFU) (CE-IVD) – (Italian)
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