264,00 € – 414,00 €
This antibody reacts with the CD117 antigen, which is expressed within the haematopoeitic compartment on approximately 50 % of CD34+ progenitors engaged in erythrocytic, myelo-monocytic and megakaryocytic differentiation. The 104D2 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation.
|Storage||Store in the dark at 2-8°C.|
Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor.
The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).
MOLM-1 megakaryocytic cell line.
Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.