Anti-Human IgM (MHM-88)

SKU: IGMPP5.5-25T Category:

175,00 € excl.VAT

IgM is the first antibody produced in a primary immune response and circulates mainly as a high-avidity pentamer. It efficiently activates the classical complement pathway and is also expressed on naïve B cells as part of the B-cell receptor. Anti-human IgM monoclonal antibodies specifically recognize the μ heavy chain and are widely used in flow cytometry and immunofluorescence to identify IgM+ B cells in studies of B-cell maturation, immune function, and related disorders.

Additional information

Regulatory Status

Gene ID

Species Reactivity

Conjugated

Storage Store in the dark at 2-8 ºC
Other names

IGHM, Immunoglobulin M
Buffer

Aqueous buffered solution containing protein stabilizer and 0.09% sodium azide (NaN3).
Immunogen

Human Ig cocktail

Recomended usage

Immunostep’s anti-human IgGM, clone MHM-88, is a monoclonal antibody intended for the identification of cells expressing IgM protein in peripheral blood using a compatible flow cytometer. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 1 test for 106 cells or 100 l of sample. Anti-IgM should be used with wash steps before reagent addition or with ficoll gradient separation to remove Immunoglobulins from serum.

References

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