Anti-Human CD3d (BGRL11)

This antibody reacts with the C3d antigen, a fragment derived from the cleavage of complement component C3. The C3d fragment remains covalently bound to the surface of target cells or pathogens following complement activation, serving as an important marker for immune adherence and clearance. The mouse monoclonal antibody BGRL11 specifically recognizes this human complement fragment C3d. The antigen is a key physiological ligand for complement receptor 2 (CR2/CD21), facilitating the bridging of innate and adaptive immunity by enhancing B-cell activation and antibody production.