CD203c

SKU: 203CPE2-100T Category:

565,00 € excl.VAT

The monoclonal antibody NP4D6 specifically binds to CD203c (ENPP3), a type II transmembrane glycoprotein with enzymatic activity. CD203c is expressed on basophils and mast cells, and is markedly increased on activated basophils following allergen or IgE stimulation, making it a reliable marker of basophil activation in type I allergies. Its expression has also been observed in neoplastic cells in systemic mastocytosis, secretory endometrial glands and glioma cells. Flow cytometry with the NP4D6 clone is widely used in the diagnosis and monitoring of allergies, mast cell disorders and immunophenotyping studies.

Additional information

Clonality

Conjugated

Isotype

Regulatory Status

Format

Size

Storage Store in the dark at 2-8 ºC
Other names

E-NPP3, ENPP3
Buffer

Aqueous buffered solution containing protein stabilizer and 0.09% sodium azide (NaN3).
Immunogen

Human CD203c Transfected Cell Line

Recomended usage

Immunostep’s CD203c, clone NP4D6, is a monoclonal antibody intended for the identification and analysis of human basophils and mast cells expressing the CD203c antigen using flow cytometry. CD203c is a type II transmembrane ectoenzyme upregulated upon cell activation, making this antibody a valuable tool for studying allergic responses, basophil activation, and mast cell-related disorders. This antibody is designed for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis using 1 test for 10 6 cells.

Resources

Technical Data Sheet (TDS) (RUO) – (English)

References

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