Exosomes are small extracellular vesicles that are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body (MVB), with the plasma membrane. They are thought to provide a means of intercellular communication and of transmission of macromolecules between cells allowing the spread of proteins, lipids, mRNA, miRNA and DNA and as contributing factors in the development of several diseases. Exosomes can also modulate cancer microenvironment and the immune response.
Lyophilized exosomes can be stored between 2ºC and 8ºC for up to 2 years without functional compromise.
Content kit
Lyophilized Exosomes from PANC-1, a human pancreas cancer cell line.
Buffer
Lyophilized exosomes (1×10^12) from derived from human cancer cell line.
For reconstitution, we recommended adding sterile, distilled water to achieve a final exosome concentration of 1μg/μl.
Recomended usage
To be used as standards or controls for exosomes assays.