CD21

SKU: P21F-100T Categories: ,

203,15  excl.VAT278,05  excl.VAT

This antibody reacts with the CD21-antigen, which reacts with the C3d complement fragment and with Epstein Barr virus (EBV) receptors, found on mature B cells, follicular dendritic cells, andsome epithelial cells. It is also weakly expressed on a subset of mature T cells and thymocytes.
This clone also cross-reacts with a major subset of, but not all, peripheral blood CD20 + lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. A subset of CD3 + cells is also CD21 +. The monoclonal antibody is directed against the CD21-antigen, which is expressed on normal Ig-positive B-cells from peripheral blood and lymphoid tissues and on dendritic cells of germinal centres. Its expression is lost on activated B-cells. The distinct distribution among B-cell malignancies differs from other B-cell markers e.g. CD19 and CD20.

Additional information

Conjugated

, ,

Size

Regulatory Status

,

Clone

Gene ID

Format

Species Reactivity

Isotype

Tested Applications

Clonality

UniProt

Mw

Population

B- Cell, Dendrititic Cell, Epithelial Cell, Stem Cell/Precursor, T-Cell

Storage Store in the dark at 2-8°C.
Other names

Complement receptor type 2 (Cr2), Complement C3d receptor, Epstein-Barr virus receptor (EBV receptor), C3DR.

Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).

Immunogen

Tissue / cell preparation (Human).

Concentration

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.