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Granzyme B is able to induce target cell apoptosis by activating caspase independent pathways. Granzyme B is induced in CD8+ T lymphocytes with ConA/ IL-2 and CD4+ T lymphocytes with anti CD3/CD28 or CD3/CD46.
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| Almacenamiento | Store in the dark at 2-8°C. |
| Otros nombres | CTLA-1, Granzyme-2. |
| Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3). |
| Immunogen | Human NK cell line YT-INDY-derived granzyme B. |
| Concentración | 0,05 mg/ml |
Immunostep’s granzyme B, clone GB11, is a monoclonal antibody intended for the identification of apoptosis in the target cells by activation of caspases using flow cytometry
Technical Data Sheet (TDS) – (English). Safety Sheet (MSDS) – (English)
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