CD56

SKU: P56PE2-100T Categorías: ,

319,01  excl.VAT362,79  excl.VAT

This antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.

Información adicional

Conjugated

,

Size

Regulatory Status

Clone

Gene ID

Format

Species Reactivity

Isotype

Tested Applications

Clonality

UniProt

Mw

Almacenamiento Store in the dark at 2-8°C.
Otros nombres

Leu-19, NKH1, NCAM, CAMPATH-1 antige, CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, Human epididymis-specific protein 5.

Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).

Immunogen

KG-1 human acute myelogenous leukemia cell line.

Concentración

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.