CD3/CD16+56/CD45

SKU: 3F11656PE45PP1-50T Categorías: ,

358,62  excl.VAT

The CD3 monoclonal antibody is directed against the CD3- antigen (T3-antigen), which is expressed on human T lymphocytes. The monoclonal antibody reacts with 80-90% human peripheral T lymphocytes and medullary thymocytes. The monoclonal antibody does not react with B-cells, monocytes, granulocytes and platelets.
This CD16 PE, clone 3G8 monoclonal antibody reacts with human CD16, which is also known as the low-affinity FcγRIII. CD16 exists as two distinct isoforms, FcγRIIIA and FcγRIIIB. In humans, FcγRIIIA is expressed as a polypeptide- anchored form on monocytes, macrophages, and lymphocytes such as NK cells. T and B cells do not express this Fc receptor.
FcγRIIIB is also detected on neutrophils as a GPI-anchored form. Expression of CD16 on lymphocytes and monocytes is similar in non-human primates.
CD56, expression of neural cell adhesion molecules (N-CAM) provides neurons with a means of attaching to and interacting with other cells and the extracellular matrix.
The CD45 monoclonal antibody is directed against the CD45-antigen, defined T200 or Leucocyte Common Antigen. The antibody reacts with all cells of the haemopoietic lineage, not with cells of other lineages.

Información adicional

Conjugated

Size

Clone

Format

Species Reactivity

Isotype

Tested Applications

Regulatory Status

Almacenamiento Store in the dark at 2-8°C.
Buffer

The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3).

Immunogen

The anti-CD3 monoclonal antibody derives from human leukocytes.
The Mouse anti-human CD16 monoclonal antibody derives from human polymorphonuclear leukocytes. The anti-CD56 monoclonal antibody derives from Human U937 cell line.
The anti-CD45 monoclonal antibody derives from T cells from leukemic HPB-ALL.

Concentración

Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml.