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This antibody reacts with the CD11c antigen. Human CD11c (alpha X integrin) complexes with CD18 (beta2 integrin) to form the complement receptor type 4 (CR4) heterodimer which binds to fibrinogen and is involved with monocyte/granulocyte adhesion during inflammatory responses. CD11c expression is restricted to leukocytes mainly of myeloid lineage with highest expression on macrophages.
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Almacenamiento | Store in the dark at 2-8°C. |
Otros nombres | CR4, p150, 95, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150. |
Buffer | The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide (NaN3). |
Immunogen | Synovial fluid dendritic cells. |
Concentración | Please refer to the Certificate of Analysis for the lot-specific concentration. Typically 0,05 mg/ml. |
CD11c, clone BU-15, is a mAb intended for the identification/enumeration of human leucocytes using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.
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