Exosomes are small extracellular vesicles that are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body (MVB) 1 , with the plasma membrane. They are thought to provide a means of intercellular communication (2,3) and of transmission of macromolecules between cells allowing the spread of proteins, lipids, mRNA, miRNA and DNA and as contributing factors in the development of several diseases. Exosomes can also modulate cancer microenvironment (4) and the immune response (5,6) .Fluorescent exosomes are labelled by expressing a specific exosome membrane marker (such as CD63) fused to a fluorescent protein (i.e. EGFP) in 293F cells.<\/p>\n","protected":false},"excerpt":{"rendered":"
Exosomes are small extracellular vesicles released when multivesicular bodies fuse with the plasma membrane. They mediate intercellular communication by transferring proteins, lipids, mRNA, miRNA, and DNA, and can influence disease progression, the cancer microenvironment, and immune responses. Fluorescent exosomes can be generated by expressing a membrane marker like CD63 fused to a fluorescent protein (e.g., EGFP) in 293F cells.<\/p>\n","protected":false},"featured_media":37984,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_links_to":"","_links_to_target":""},"product_line":[189],"product_cat":[2181],"product_tag":[],"class_list":{"0":"post-37930","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_line-exosomes","7":"product_cat-lyophilized-exosomes","8":"pa_conjugated-bfpcd9","9":"pa_conjugated-egfpcd63","10":"pa_conjugated-mscarletcd81","11":"pa_format-lyophilized","12":"pa_regulatory-status-ruo","13":"pa_size-30-g","14":"pa_species-reactivity-human","15":"pa_tested-applications-fcm","16":"pa_tested-applications-nta","18":"first","19":"instock","20":"taxable","21":"shipping-taxable","22":"purchasable","23":"product-type-variable"},"yoast_head":"\n