Antibody CD59 (Clone MEM-43) reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a GPI-anchored molecule, in T cell activation. Appears to have some role in cell adhesion through CD2 (controversial).<\/p>\n","protected":false},"excerpt":{"rendered":"
Antibody CD59 (Clone MEM-43) reacts with the CD59-antigen, a PI-linked glycoprotein, molecular weight 18-20kDa, found in all types of leukocytes including platelets. Antigen distribution is to be found across many hemopoietic and non-hemopoietic cells. CD59 inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis Has a signaling role, as a […]<\/p>\n","protected":false},"featured_media":26938,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_links_to":"","_links_to_target":""},"product_line":[2167,2166],"product_cat":[],"product_tag":[],"class_list":{"0":"post-22069","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_line-immunology","7":"product_line-oncohematology","8":"pa_clonality-monoclonal","9":"pa_clone-mem-43","10":"pa_conjugated-pe","11":"pa_format-liquid","12":"pa_gene-id-1895","13":"pa_isotype-igg1","14":"pa_mw-18-20kda","15":"pa_protocol-sm","16":"pa_regulatory-status-ruo","17":"pa_size-100-test","18":"pa_size-1-mg-ml","19":"pa_size-2-mg-ml","20":"pa_species-reactivity-human","21":"pa_tested-applications-fcm","22":"pa_uniprot-p13987","24":"first","25":"instock","26":"taxable","27":"shipping-taxable","28":"purchasable","29":"product-type-simple"},"yoast_head":"\n